Designing a well-built question will help dictate the development of your searching strategy. With PICO, you can identify the the main components of your research question. According to the Cochrane Handbook for Systematic Reviews of Interventions (2020), "Population, interventions and comparators in the review question usually translate directly into eligibility criteria for the review" although this is not always a straightforward process. These components should be sufficiently broad in order to accomodate a diversity of literature . At the same time, they should also be sufficiently narrow to ensure that a meaningful answer can be obtained when the literature is assessed and synthesized. The Cochrane Handbook includes suggestions for factors to consider when developing criteria for your PICO components.
Patient/Population/Problem
Intervention and Comparison
Outcomes
These recommendations are meant to provide users with direction regrading what they should incorporate into their final PICO. If you are encountering issues with identifying suitable PICO components, do not hesitate to reach out to your librarian for assistance.
The preliminary search is a non-systematic research meant to help you familiarize yourself with the scope of available literature, identify key terms and appropriate synonyms, and locate prospective grey literature.
During this phase, researchers should begin recording relevant and related search terms/concepts that they may incorporate into their final strategy. These terms and concepts will help ensure that your search retrieves as many relevant results as possible:
Controlled vocabularies (such as the MESH subject headings used in Medline/PubMed) provide an organized approach to the way knowledge is described. Using the same terminology throughout a database creates consistency and precision and helps you to find relevant information no matter what terminology the author may have used within their publication. Check out this tutorial from the National Library of Medicine to learn more about MeSH. Click here to learn more about MeSH and how to find MeSH terms in PubMed.
During the preliminary search, you should familiarize yourself with the searching techniques that you'll be incorporating into your search. These include:
After running your preliminary searches, you should have a clear sense of what relevant literature is available along with what search terms you should include in your final search strategy. When you are ready to start systematically searching for literature, it is important to take each step in the process slowly:
If your final search strategy is not yielding appropriate or suitable results, there is always a possibility that it needs revision. This is a common part of the systematic review process. See the next tab for more information.
Returning to the drawing board to revise a search strategy is a common part of the systematic review process. Two of the most commons reasons that a search strategy may need to be revised is 1). it is producing Too Few Results or 2). it is producing Too Many Results. Additionally, your research question or needs may have changed as your research project has evolved.
If you are getting very few results, or none at all, you should try making your search broader.
It is important to note that there are occasions when there simply isn't much available literature on a given topic. If this occurs, do not hesitate to reach out to the Netter librarians for assistance. They can offer guidance on how to readdress your topic and search strategy.
If you have a large number of results but not many of them look relevant, you may need to make your search more specific.
If you do have to revise your search strategy, you will likely have to restart the screening process. Although this may be a bit frustrating, keep in mind that searching is an iterative process that often takes multiple attempts before reaching a final search strategy.
Adapted from: UConn Library's Find Information -- Revising & Refining your Search | Washington University in St. Louis University Libraries' Creating & Revising your Search Strategy
Although there is no defined "stopping" point, keep the following in mind:
Do note, if this is a long-term research project, be prepared to re-run your searches once every three or four weeks. You want to be sure that you are on top of the latest research.