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Module 4: Literature Search Strategy

General Search Strategy for Databases

The following steps outline a general search strategy for databases. 

1. Identify key concepts

For clinical questions, PICO framework can help you to identify the main concepts. For general research questions or when PICO doesn't apply, find the nouns in your research question, then pick the key concepts. As most often, concepts are nouns. In addition, thinking about what key concepts the articles should include in the search results.

2. Collect search terms

When collecting search terms, include keywords/free text that authors might use to describe the same concept, and controlled vocabularies in the search. Use Boolean OR to combine the terms. 

With keywords, you can search using natural language, but you also want to be thorough and try using several variations of the concept you are searching for. Common keyword variations to consider:

  • Synonyms - toddler, preschooler, child

  • Singular and plural versions of terms - child, children

  • International spellings - pediatric & paediatric
  • Acronyms - MRI & magnetic resonance image
  • Related terms from other fields

Controlled vocabularies are standardized and organized arrangements of words and phrases and provide a consistent way to describe data. Metadata creators assign terms from vocabularies to improve information retrieval. Medical Subject Heading, or MeSH, is the NLM controlled vocabulary thesaurus used for indexing articles in PubMed, MEDLINE, Cochrane Reviews and part of their clinical trials, and CINAHL (CINAHL has its own subject headings, but accepts MeSH as the standard vocabulary for disease, drug, anatomical, and physiological concepts). Not every database has controlled vocabulary, like Scopus, it doesn't use any controlled vocabulary. 

Why Include Controlled Vocabularies in the search? 

MeSH group terms into concepts, or in other words, multiple alternative words for the same concept can be retrieved by using the MeSH term. See examples below:

If you search MeSH term "otitis media", in the search result, you should be able to see articles that use any of the following terms: middle ear inflammation, middle ear infection, otitis media if the article was indexed by the MeSH term "otitis media". 

If you search MeSH term "Neoplasms", in the search result, you will see any of the following terms: tutor, tumors, cancer, cancers, neoplasm, etc. 

3. Search each concept separately.

Sometimes you need to adjust the search, like use less concepts when you have fewer results. If you search each concept separately, it will be easier to combine as less or as many concepts as you wish.

4. Combine concepts.

Use Boolean AND to combine difference concepts. 

5. Apply filters.

Use age, gender or study types filters as needed. In PubMed, you will see filters like systematic review, RCTs, observational studies, etc under the ARTICLE TYPE filer. 

Search Basics

Keywords, also known as search terms are the words that you enter into database search boxes. They represent the main concepts of your research project.

Keywords summarized:

  • Natural language terms used to describe your topic
  • Can be combined a number of ways with Boolean Operators -- see the next tab to learn more!
  • Used when no appropriate subject heading exists

When searching in databases, keywords can be used to...

  • Search for singular and plural terms together
  • Search for terms with different spellings
  • Search for abbreviations
  • Search for synonyms of terms together
  • Search for phrases inside of quotation marks

Searching is an iterative process that will take trial and error. Be patient -- you'll find the right words to use.

Boolean operators are words (AND, OR, and NOT)  that are used as conjunctions to include or exclude keywords in a search. Their use leads to more focused and precise results. These operators help string your search terms together. combining them effectively. Most databases utilize boolean operators for searching. 

AND
  • Use to combine together separate topics -- tip: think of AND as a plus (+) sign
  • Both terms will be present in your search results
  • Narrows your search results
  • Finds results that include ALL of your terms
  • Examples
    • Cat AND Dog
    • Exercise AND Heart Attacks
OR
  • Use to connect synonyms or related ideas
  • Expand your search results
  • One or more of your terms may appear in the search results
  • Finds results that include ANY of your terms
  • Examples: 
    • Cat OR Dog
      • Exercise OR Workout OR Aerobics
NOT
  • Use to remove terms from the search results
  • Narrows your search
  • Further defines your term -- good for terms that might have multiple meanings 
  • Examples:
    • Cat NOT Dog
    • Nursing NOT breastfeeding 

Phrase searching includes placing quotation marks ("__") around two or more words to create a search term.  This searching technique dictates to the database to retrieve only those results in which the exact phrase appears.

  • Also known as quotation searching 
  • Useful when paired with OR
  • The quotations "lock" in your terms and tell the database to retrieve results that have your terms appear exactly as they do in the quotations

A search for attention deficit disorder = attention AND deficit AND disorder  -- without phrase searching

A search for "attention deficit disorder" = "attention deficit disorder" -- with phrase searching

Note: Phrase searching in individual databases may vary. Check the help pages in each database for additional information.

Consider using synonyms and abbreviations to enhance your searching. The English language is filled with many different ways of saying the same thing. Using synonyms and abbreviations while searching in databases will help ensure that you are able to create a comprehensive search string that will capture all relevant articles.

Synonyms 

Synonyms are words that have the same or similar meaning to another word or phrase. Many concepts have different terms that can be used to describe them. For example, some additional keywords that can be used for Pediatric Obesity include:

  • Child obesity
  • Childhood obesity
  • Adolescent obesity
  • Obesity, child
  • Obesity in adolescence
  • Childhood onset obesity
  • Childhood overweight

If you are not sure how to find synonyms for your terms, try looking in PubMed's MeSH (medical subject headings) database. Most entries in the MeSH database include a list of 'Entry Terms'. These are all the terms that you could search that would be still ultimately connect to a specific MeSH term in PubMed. 

Abbreviations 

When searching, you should always spell out any abbreviations that might be included among your search terms. For example, if yoy are searching for articles on PTSD, you should spell out the phrase, post-traumatic stress disorder, as well as include the abbreviation. 

Truncation, also called stemming, is a technique that broadens your search to include various word endings and spellings.

  • Uses a symbol to search for all possible forms of a word
  • Frequently used symbols include asterisk (*), a question mark (?), or a dollar sign ($)
  • Broadens your search
  • Useful to find alternate endings or plural form of a word
  • Different databases use different symbols. Check the database's 'Help' or 'Search tips' pages for details on which symbol to use
Example:

Child* = child, child's, childhood, children, children's, 

Some important things to note about truncation:

  • The placement of the truncation symbol can impact the type of results you get back
  • Some databases may have a minimum requirement for how long a term must be in order to use truncation
  • Truncating a search term in PubMed disables automatic term mapping, meaning synonyms and MeSH terms will not be added to your search.
Truncation in practice

 If I searched toxic* in PubMed, my search results would include.... 

  • Toxic
  • Toxicity 
  • Toxicology

 Wildcards are another searching technique. They are used in search terms to represent one or more other characters.

  • Use symbols to represent a letter or letters in a word
  • Broadens your search
  • Useful when searching with words that have different spellings
  • Frequently used wildcard symbols include question marks (?), the pound symbol (#), or the asterisk (*)
Examples:
  • wom#n = woman or women
  • col?r = color or colour
Some important things to note about using Wildcard while database searching:
  • Different databases use different symbols. Check the database's 'Help' or 'Search tips' pages for details on which symbol to use
  • Some databases may have minimum requirements for how long a term has to be use Wildcard